What It Is
MOTS-c is a naturally occurring 16-amino acid peptide encoded within the mitochondrial genome. Unlike most peptides that originate in nuclear DNA, MOTS-c comes from the mitochondria, the cell’s powerhouses.
Research has shown that MOTS-c can regulate metabolic processes, enhance insulin sensitivity, and activate stress response pathways that support cellular energy production. It is of particular interest in studies related to metabolism, aging, and resilience under physical or metabolic stress.
Benefits (Research Has Shown)
- Supports Metabolic Health: Research has demonstrated MOTS-c may improve insulin sensitivity and regulate glucose metabolism.
- Weight Management: Animal and human studies suggest it can influence fat metabolism and promote weight reduction pathways.
- Exercise & Performance: Some findings indicate MOTS-c may increase endurance and exercise capacity by optimizing mitochondrial function.
- Cellular Stress Resistance: Research shows MOTS-c activates AMPK pathways, helping cells adapt to metabolic stress.
- Anti-Aging Potential: Investigations link MOTS-c to longevity pathways, with studies suggesting it may counteract age-related declines in energy.
Who Might Use It
- Metabolic researchers: Studying obesity, diabetes, or metabolic syndrome.
- Sports science groups: Exploring enhanced endurance, energy, and performance recovery.
- Longevity researchers: Investigating mitochondrial health and aging interventions.
- Neuroscience studies: Some research suggests possible neuroprotective effects due to improved energy metabolism.
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