What It Is
Tesofensine is a triple monoamine reuptake inhibitor (SNDRI) originally developed for neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. By inhibiting the reuptake of serotonin, norepinephrine, and dopamine, Tesofensine increases the levels of these neurotransmitters in the brain.
Research has since shifted toward its effects on appetite regulation and weight management. Clinical studies have shown Tesofensine may significantly reduce body weight by influencing hunger centers in the brain, while also enhancing energy expenditure.
Benefits (Research Has Shown)
- Weight Loss Support: Clinical trials indicate Tesofensine can reduce appetite and caloric intake, leading to significant weight reduction.
- Cognitive Function: Research has suggested Tesofensine may support dopamine and norepinephrine pathways tied to alertness and focus.
- Energy & Metabolism: Some studies note increased resting energy expenditure, contributing to weight management.
- Mood Regulation: Through serotonin modulation, Tesofensine has been investigated for potential mood-enhancing effects.
- Neuroprotective Interest: Early research considered Tesofensine for neurodegenerative conditions, highlighting its impact on neurotransmission.
Who Might Use It
- Obesity researchers: Studying agents that influence appetite and weight reduction.
- Neuroscience teams: Exploring neurotransmitter-modulating compounds for cognitive and mood research.
- Metabolic health studies: Interested in compounds that regulate both caloric intake and energy expenditure.
- Longevity research groups: Looking at peptides and compounds that support healthier body composition over time.
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